Pure Nutrition Folic Acid is a unique formula that contains bioactive forms of vitamin B9/folate (as folic acid) and vitamin B12 (as cyanocobalamin) for enhancing nervous system function, cardiovascular health, energy production, homocysteine balance and a variety of other health processes.
Clinical studies suggest that deficiencies in several of the B vitamins, especially folate and vitamin B12, accelerates brain tissue atrophy and cognitive decline.1 In fact, a contemporary clinical trial showed that supplementing with folic acid and vitamin B12 is effective for boosting cognitive function and inhibiting neurodegenerative processes.2
Since many people lack vegetable and fruit intake, supplementing with Pure Nutrition Folic Acid is a great way to avoid deficiency of these key B vitamins. Pure Nutrition Folic Acid is also ideal for prenatal support, as pregnant women need upwards of eight times as much folic acid as females who are not carrying.
Folic acid (folate) is necessary for nearly every physiological reaction in the body that includes a one-carbon transfer. When you ingest folic acid, various enzymes convert it to its biologically active form - L-5-methyltetrahydrofolate (5-MTHF).
Pure Nutrition Folic Acid contains a high dose of pure folic for encouraging healthy folate status and 5-MTHF activity. This is especially crucial for people who lack folate intake through food and pregnant women.
Furthermore, Pure Nutrition Folic Acid contains an ample dose of synergistic vitamin B12, which works in conjunction with folic acid to support DNA synthesis/replication, as well as the synthesis of hemoglobin - an essential protein found in red blood cells that transports carbon dioxide and oxygen throughout the body.
In terms of biochemistry, Vitamin B12 (cobalamin) is the most complex of all vitamins and plays a key role throughout the nervous system. Along with folic acid, vitamin B12 helps synthesize DNA and is involved in the metabolism of all proteinogenic amino acids in the body. Due to its intricate and complex nature, vitamin B12 is the most common B vitamin for humans to be deficient in.
Research shows that a deficiency of vitamin B12 can lead to serious, irreversible health ramifications, including pernicious anemia (lack of red blood cell production) and damage to the brain and nervous system.3 This is why people who lack vitamin B12 are at an increased risk for conditions like Alzheimer’s disease and dementia.
Moreover, vitamin B12 is necessary for helping your body convert for homocysteine to methionine; methionine is necessary for the synthesis of S-adenosylmethionine (SAMe) - a molecule that helps create catecholamines and various other neurotransmitters. As such, by supporting SAMe levels, vitamin B12 is integral to enhancing mood and cognition, as deficiencies can lead to high levels of anxiety and major depression.4
Both folic acid and vitamin B12 play pivotal roles in supporting healthy nervous and cardiovascular system function. Moreover, these B vitamins work in concert for proper DNA maintenance, energy production, cellular respiration, hormone production, and a variety of other processes.
Research and clinical evidence cited herein demonstrate that the B vitamins in Pure Nutrition Folic Acid can:
Pure Nutrition Folic Acid is made in a cGMP facility in the USA. It is also free of wheat/gluten, soy, shellfish, milk, egg, tree nuts, artificial colors, and GMOs. Be wary of vitamin supplements that are manufactured in unsanitary environments and contain low-grade raw ingredients. Pure Nutrition Folic Acid also contains a high-dose of both folic acid (800 mcg) and vitamin B12 (25 mcg) to ensure you get a clinically effective dose with each serving.
Endnotes
1. Van Uffelen, J. G., Chinapaw, M. J., van Mechelen, W., & Hopman-Rock, M. (2008). Walking or vitamin B for cognition in older adults with mild cognitive impairment? A randomized controlled trial. British journal of sports medicine.
2. Eussen, S. J., de Groot, L. C., Joosten, L. W., Bloo, R. J., Clarke, R., Ueland, P. M., ... & van Staveren, W. A. (2006). Effect of oral vitamin B-12 with or without folic acid on cognitive function in older people with mild vitamin B-12 deficiency: a randomized, placebo-controlled trial. The American journal of clinical nutrition, 84(2), 361-370.
3. HU, R. (2015). Vitamin B12 deficiency. European Journal of General Medicine, 12(3).
4. Penninx, B. W., Guralnik, J. M., Ferrucci, L., Fried, L. P., Allen, R. H., & Stabler, S. P. (2000). Vitamin B12 deficiency and depression in physically disabled older women: epidemiologic evidence from the Women’s Health and Aging Study. American Journal of Psychiatry, 157(5), 715-721.
| Supplement Facts | |
| Servings | 250 tablets |
| Amount per Serving | |
| Folate | 1,333.33 mcg DFE |
| Vitamin B12 (Cyanocobalamin) | 25 mcg |
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©2018 Pure Nutrition, Inc
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. For best results supplements should be taken as directed over time, at maximum dosage in conjunction with a healthy diet and regular exercise program. Results may vary.